First thing I would try is to use another browser. Chrome has been more picky about HTTPS lately (for good reasons).
What is the exact error message you get? What does a google search for that suggest?
I tried a quick search for chrome cipher mismatch (which is all you gave us to work with til now) and it came up with both suggestions for what to try on chrome itself but also e.g. stuff pointing to the certificate and not cipher mismatches like https://community.spiceworks.com/topic/857680-err_ssl_version_or_cipher_mismatch-on-internal-website-only-on-chrome
A cipher mismatch btw is that the server and browser do not agree on one of the “cipher suites” they both offer to work with. I usually use https://www.ssllabs.com/ssltest/ for investigating if HTTPS is setup correctly on a server. It has a section on what cipher suites a server offers to work with. There are also other tools if you’re not able to expose your server to the internet.
There are ways to configure Jetty (the web server embedded into Metabase). But let’s wait going there until the problem has been narrowed down
Hope this helps for a start. Now tell us what you tried of the above and what outcome it gave. Then we can take it from there!